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Can infants be protected by means of maternal vaccination? [Article de Revue]

 
[Les nourrissons peuvent-ils être protégés par la vaccination maternelle ?]
BOSIS S ; MORLACCHI L ; BAGGI E ; SABATINI C ; Esposito, S ; PRINCIPI N
Clinical microbiology and infection. 2012/10; 18(Supplement 5) : 85-92
Summary: The administration of vaccines is not usually recommended in pregnant women because of a fear of severe adverse events for the fetus. However, contraindication to vaccination applies only to vaccines based on live attenuated viruses for the theoretical possibility that they might infect the fetus. On the contrary, the use of several inactivated vaccines is useful and recommended. As a result of the transplacental passage of antibodies, maternal immunisation can reduce the risk of vaccine-preventable diseases that may occur in the first months of life before the start or completion of the suggested vaccination schedule. One of the best examples is vaccination against influenza that can protect pregnant women from a disease that can lead to hospitalisation and death in a significantly higher number of case than in the general population and can induce protective specific antibody levels as well as can be effective in infants in the first months of life. Other examples are vaccinations against tetanus, pertussis, pneumococcal infections and Haemophilus influenzae type b infection. This review analyses the advantages and limitations of maternal immunisation as revealed by experience and the main publications.
(RESUME D'AUTEUR)
Publication
2012/10

Pages
85-92

Language
Anglais

Number of ref
74

Published in
Clinical microbiology and infection

ID notice
319001

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