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Impact of chlorhexidine bathing on hospital-acquired infections among general medical patients [Article de Revue]

 
[Impact de la toilette quotidienne à la chlorhexidine sur les infections nosocomiales chez des patients en médecine générale]
Kassakian, Steven Z ; Mermel, Leonard A ; JEFFERSON JA ; PARENTEAU SL ; Machan, Jason T
Infection control and hospital epidemiology. 2011/03; 32(3) : 238-243
Summary: Background: A paucity of data exists regarding the effectiveness of daily chlorhexidine gluconate (CHG) bathing in non.intensive care unit (ICU) settings.Objective: To evaluate the effectiveness of daily CHG bathing in a non-ICU setting to reduce methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enteroccocus (VRE) hospital-acquired infections (HAIs), compared with daily bathing with soap and water.Design: Quasi-experimental study design; the primary outcome was the composite incidence of MRSA and VRE HAIs. Clostridium difficile HAI incidence was measured as a nonequivalent dependent variable with which to assess potential confounders.Setting: Four general medicine units, with a total of 94 beds, at a 719-bed academic tertiary-care facility in Providence, Rhode Island.Patients: A total of 7,102 and 7,699 adult patients were admitted to the medical service in the control and intervention groups, respectively. Patients admitted from January 1 through December 31, 2008, were bathed daily with soap and water (control group), and those admitted from February 1, 2009, through March 31, 2010, were bathed daily with CHG-impregnated cloths (intervention group).Results: Daily bathing with CHG was associated with a 64% reduced risk of developing the primary outcome, namely, the composite incidence of MRSA and VRE HAIs (hazard ratio, 0.36 [95% CI, 0.2.0.8]; ). There was no change in the incidence of C. difficile HAIs (). Colonization with MRSA was associated with an increased risk of developing a MRSA HAI (hazard ratio, 8 [95% CI, 3.19]; ).Conclusion: Daily CHG bathing was associated with a reduced HAI risk, using a composite endpoint of MRSA and VRE HAIs, in a general medical inpatient population.(RESUME D'AUTEUR)
Publication
2011/03

Pages
238-243

Language
Anglais

Number of ref
14

ID notice
319187

Location Call number Status Date due Barcode
CCLIN Est
CClin Est
CHU de Nancy - Hôpitaux de Brabois
Rue du Morvan
54511 Vandoeuvre le Nancy Cedex
Tél : 03.83.15.34.73
cclin.est@chu-nancy.fr
http://www.cclin-est.org/
CCLIN Ouest
CClin Ouest
CHU Hôtel Dieu
CS 26419
35064 Rennes Cedex 2
Tél : 02.99.87.35.31
isabelle.girot@chu-rennes.fr
http://www.cclinouest.com/
CCLIN Paris Nord
CClin Paris-Nord
96 rue Didot
75014 Paris
Tél : 01.40.27.42.00  
karin.lebascle@sap.aphp.fr
http://www.cclinparisnord.org/
CCLIN Sud-Est
CClin Sud-Est
Hospices Civils de Lyon
Hôpital Henry Gabriel
20 route de vourles
69230 Saint-Genis-Laval
Tél : 04.78.86.49.50
cclinse@chu-lyon.fr
http://cclin-sudest.chu-lyon.fr/
CCLIN Sud-Ouest
CClin Sud-Ouest
CHU de Bordeaux
Hôpital Pellegrin - Bâtiment Le Tondu
33076 Bordeaux
Tél : 05.56.79.60.58
cclin.so@chu-bordeaux.fr
http://www.cclin-sudouest.com/

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